Studies on Haemonchus contortus. VIII. Attempts to protect suckling lambs against infestation with H. contortus.
نویسندگان
چکیده
A group of 12 Merino lambs, 3,5 months of age, which were still suckling, were each dosed with 40 000 infective larvae of Trichostrongylus axei on Day 0. From Day +62-Day 64 each of these lambs and those of a 2nd group of 11 controls were dosed with 30 000 infective larvae of Haemonchus contortus, and all the lambs of both groups were killed on Day +90. Attempts to use T. axei to protect them against subsequent challenge with H. contortus were unsuccessful.
منابع مشابه
Studies on Haemonchus contortus. VI. Attempts to stimulate immunity to abomasal trichostrongylids in Merino sheep.
Two doses of infective larvae of 20 000 Trichostrongylus axei, dosed to Merino lambs at an interval of 14 days and subsequently challenged with Ostertagia circumcincta, caused a significant reduction (P less than 0.01) in the establishment of 5th and adult stages of the latter. T. axei was unable to protect Merino sheep against homologous challenge nor was Haemonchus contortus a successful vacc...
متن کاملStudies on Haemonchus contortus. II. The effect of abomasal nematodes on subsequent challenge with H. contortus.
Fifty-thousand infective larvae of Trichostrongylus axei dosed to 7-9-month-old Merinos protected them against a subsequent challenge with 50 000 infective larvae of Haemonchus contortus. Protection varied with the period between an initial dosage of T. axei and challenge with H. contortus as follows: After 90 days it was more than 80% effective in more than 80% of sheep; at 119 and 180 days th...
متن کاملStudies on Haemonchus contortus. I. The influence of previous exposure to Trichostrongylus axei on infestation with H. contortus.
REINECKE, R. K. Studies on Haemonchus contortus l. The influence of previous exposure to Trichostrongylus axei on infestation with H . cantor/us. Onderstepoort J. vet. Res. 41 (4) , 213216 (1974) . A group of Merino sheep, aged 67 months was infested orally with 50 000 infective larvae of Trichostrongylus axei. This group and a control group were challenged 9092 days later with 50 000 infective...
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Lambs vaccinated with Haemonchus contortus excretory/secretory (ES) glycoproteins in combination with the adjuvant Alhydrogel are protected against H. contortus challenge infection. Using glycan micro-array analysis we showed that serum from such vaccinated lambs contains IgG antibodies that recognise the glycan antigen Galalpha1-3GalNAc-R and GalNAcbeta1-4(Fucalpha1-3)GlcNAc-R. Our studies rev...
متن کاملImmunization of Arabian sheep with whole gut homogenate of Haemonchus contortus
Ten female lambs of 7-month-old were divided into two equal groups and raised under a helminth-free conditions. Animals in group 1 were immunized two times by whole gut homogenate (WGH) of Haemonchus contortus emulsified in Freund’s adjuvant. In group 2 (control), animals were injected by phosphate buffered saline emulsified in the same adjuvant. Animals were challenged by 10000 third-stage lar...
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ورودعنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 49 3 شماره
صفحات -
تاریخ انتشار 1982